Premium
Assignment of the human fast skeletal muscle troponin C gene (TNNC2) between D20S721 and GCT10F11 on chromosome 20 by somatic cell hybrid analysis
Author(s) -
TOWNSEND P. J.,
YACOUB M. H.,
BARTON P. J. R.
Publication year - 1997
Publication title -
annals of human genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 77
eISSN - 1469-1809
pISSN - 0003-4800
DOI - 10.1046/j.1469-1809.1997.6150457.x
Subject(s) - somatic cell , gene , chromosome , biology , genetics , skeletal muscle , microbiology and biotechnology , hybrid , somatic fusion , troponin , anatomy , medicine , botany , myocardial infarction
The chromosomal location of the human fast skeletal muscle troponin C (TNNC2) gene was determined using somatic cell hybrids. PCR‐based analysis of a ‘monochromosomal’ hybrid panel identified the presence of the TNNC2 gene on human chromosome 20 and subsequent analysis of the Genebridge4 radiation hybrid panel located the gene between D20S721 and GCT10F11 with a lod score of >3.