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Recurrent cytomegalovirus infection during pregnancy: ultrasonographic diagnosis and fetal outcome
Author(s) -
Henrich W.,
Meckies J.,
Dudenhausen J. W.,
Vogel M.,
Enders G.
Publication year - 2002
Publication title -
ultrasound in obstetrics and gynecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.202
H-Index - 141
eISSN - 1469-0705
pISSN - 0960-7692
DOI - 10.1046/j.1469-0705.2002.00705.x
Subject(s) - medicine , cytomegalovirus , fetus , pancytopenia , pregnancy , obstetrics , gestation , cytomegalovirus infection , amniotic fluid , human cytomegalovirus , antibody , herpesviridae , immunology , viral disease , virus , bone marrow , biology , genetics
Fetal infection as a consequence of recurrent disease is uncommon. We present a case of recurrent cytomegalovirus infection in the second trimester of pregnancy. Fetal infection was detected through severely abnormal findings on ultrasound examination and verified by detecting cytomegalovirus DNA in the amniotic fluid and cytomegalovirus‐specific immunoglobulin M antibodies in the fetal blood and associated pancytopenia. Because of the severity of the infection, a fatal outcome was predicted. A Cesarean section was performed at 33 + 5 weeks of gestation; the child died shortly after birth. Copyright © 2002 ISUOG