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The outcome of antenatally diagnosed talipes equinovarus
Author(s) -
Bakalis S. P.,
Sairam S.,
Patton M.,
Harrington K.,
Nicolaides K.,
Thilaganathan B.
Publication year - 2001
Publication title -
ultrasound in obstetrics and gynecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.202
H-Index - 141
eISSN - 1469-0705
pISSN - 0960-7692
DOI - 10.1046/j.1469-0705.2001.abs22-8.x
Subject(s) - medicine , congenital talipes equinovarus , population , incidence (geometry) , pregnancy , abnormality , pediatrics , obstetrics , prospective cohort study , fetus , surgery , clubfoot , deformity , physics , environmental health , psychiatry , biology , optics , genetics
Aim: Congenital talipes equinovarus is a relatively poorly studied congenital anomaly with very little information available for parents. The aim of this study is to investigate the natural history and postnatal outcome of fetal talipes detected at 18–23 weeks in a large, unselected obstetric population. Patients and methods: This is a prospective study of routine antenatal ultrasound screening in an unselected obstetric population, carried out on patients booking at three major London hospitals. Congenital talipes was classified as postural, tetralogic (associated with other congenital abnormalities) and idiopathic. Outcomes measured included termination of pregnancy, stillbirth, aneuploidy, fetal structural abnormality and neonatal death. Results: The incidence of congenital talipes was 0.11% (111/103,228) in our study population. Of these, 64.9% were live born, 31.5% were terminated, and 3.6% were intrauterine deaths. Talipes was bilateral in 60% of the cases, with an overall male to female ratio of 1.5:1. There were significant differences in the prevalence of tetralogic, idiopathic and postural talipes in the unilateral vs. bilateral talipes groups. The outcome of pregnancy was good in 97% of fetuses with a diagnosis of idiopathic and in 36% of those with tetralogic talipes. Fetuses with a diagnosis of postural talipes were postnatally found to have other abnormalities in 7% of cases. Conclusion: The outcome of antenatally detected congenital talipes is significantly worse than previously reported. The outcome of pregnancy depends on the laterality of the talipes and the presence of associated features.