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Fetal cardiac performance in uncomplicated and well‐controlled maternal type I diabetes
Author(s) -
Jaeggi E. T.,
Fouron J.C.,
Proulx F.
Publication year - 2001
Publication title -
ultrasound in obstetrics and gynecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.202
H-Index - 141
eISSN - 1469-0705
pISSN - 0960-7692
DOI - 10.1046/j.1469-0705.2001.00365.x
Subject(s) - medicine , fetus , cardiology , cardiac function curve , interventricular septum , gestational age , pregnancy , diastole , fetal echocardiography , obstetrics , heart failure , ventricle , prenatal diagnosis , blood pressure , genetics , biology
Objective To study the impact of well‐controlled, uncomplicated maternal diabetes on fetal cardiac development and performance. Methods The following variables were studied in 45 fetuses of type I diabetic women by means of mid‐ and late‐trimester echocardiography: interventricular septal thickness; aortic and pulmonary valve diameters; peak and time‐to‐peak flow velocity of the great arteries; the ratio between peak velocities during early (E) and late (A) ventricular filling at the level of the atrioventricular valves; ventricular fractional shortenings; and output. The findings were compared to age‐matched control groups of normal fetuses. Results A significant augmentation of interventricular septal thickness was demonstrated for mid‐trimester fetuses of diabetic women, which progressed further towards the end of pregnancy. However, the indices of diastolic and systolic function remained comparable between the gestational age‐matched groups. Conclusion Progressive myocardial thickening occurs commonly in mid‐ and late‐trimester fetuses of uncomplicated and well‐controlled diabetic pregnancies. The observed degree of hypertrophy is generally mild and does not affect age‐related changes in fetal cardiac function. Copyright © 2001 International Society of Ultrasound in Obstetrics and Gynecology