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Hypoechoic hepatomegaly associated with transient abnormal myelopoiesis provides clues to trisomy 21 in the third‐trimester fetus
Author(s) -
Hamada H.,
Yamada N.,
Watanabe H.,
Okuno S.,
Fujiki Y.,
Kubo T.
Publication year - 2001
Publication title -
ultrasound in obstetrics and gynecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.202
H-Index - 141
eISSN - 1469-0705
pISSN - 0960-7692
DOI - 10.1046/j.1469-0705.2001.00362.x
Subject(s) - medicine , trisomy , myelopoiesis , fetus , abnormality , chromosomal abnormality , chromosome abnormality , pathology , down syndrome , pregnancy , karyotype , chromosome , haematopoiesis , genetics , stem cell , psychiatry , gene , biology , biochemistry , chemistry
We present two cases of transient abnormal myelopoiesis associated with trisomy 21 that had hypoechoic hepatomegaly during the late fetal period. Fetal chromosomal abnormality and fetal myeloproliferative disorder should be suspected in such cases. Copyright © 2001 International Society of Ultrasound in Obstetrics and Gynecology