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Fetal transverse cerebellar diameter measurements in normal and reduced fetal growth
Author(s) -
Vinkesteijn A.S.M.,
Mulder P.G.H.,
Wladimiroff J.W.
Publication year - 2000
Publication title -
ultrasound in obstetrics and gynecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.202
H-Index - 141
eISSN - 1469-0705
pISSN - 0960-7692
DOI - 10.1046/j.1469-0705.2000.00024.x
Subject(s) - fetus , medicine , gestational age , gestation , obstetrics , fetal head , pregnancy , cerebellum , small for gestational age , transverse diameter , anatomy , biology , genetics
Objectives To establish the increase in fetal transverse cerebellar diameter (TCD) relative to gestational age during normal and restricted fetal growth; to determine the significance of TCD and TCD/AC relationship in predicting fetal outcome as expressed by perinatal mortality.Design A retrospective cross‐sectional study.Subjects Three hundred and sixty normally developing fetuses between 17 and 34 weeks of gestation and 73 growth‐restricted fetuses between 24 and 34 weeks of gestation.Methods Ultrasonographic measurements included head circumference (mm), abdominal circumference (mm) and transverse cerebellar diameter (mm). A gestational age‐related normal reference chart was produced for TCD.Results Statistically significant relationships between transverse cerebellar diameter and gestational age, abdominal circumference and head circumference were found. The normal fetal TCD exhibited a more than twofold increase in size during the second half of pregnancy. Twenty‐six per cent of the small‐for‐gestational age (SGA) fetuses displayed a reduced TCD and 82% of the SGA fetuses demonstrated raised TCD/AC values. No statistically significant difference in perinatal mortality or birth weight was found between the subsets of growth‐restricted fetuses with reduced or normal TCD; or between the subsets with normal or raised TCD/AC values.Conclusions In the normally developing fetus the TCD increases with advancing gestational age. Increased TCD/AC values are suspicious of fetal growth restriction. The perinatal mortality in growth‐restricted fetuses with a small cerebellum is increased twofold over that of other fetuses.