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F53Umbilical venous volume flow: reproducibility and developmental data
Author(s) -
Boito S.,
Struijk P. C.,
Stijnen H. R.,
Wladimiroff J. W.
Publication year - 2000
Publication title -
ultrasound in obstetrics and gynecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.202
H-Index - 141
eISSN - 1469-0705
pISSN - 0960-7692
DOI - 10.1046/j.1469-0705.2000.00015-1-53.x
Subject(s) - reproducibility , volume (thermodynamics) , medicine , fetus , gestational age , nuclear medicine , flow (mathematics) , flow velocity , biomedical engineering , pregnancy , mathematics , chemistry , geometry , chromatography , physics , biology , genetics , relaxation (psychology) , quantum mechanics
Background To determine reproducibility of volume flow components; to calculate volume flow in normal and growth restricted fetuses in a cross‐sectional study design. Method Using Labview and Imaq‐vision software, the cross‐sectional inner vessel area was traced. Vessel area (mm 2 ) and mean flow velocity (cm/s; Doppler) were multiplied to calculate volume flow (ml/min) including flow/kg fetus. The coefficient of variation (CV) for vessel area and flow velocity scans and tracings was determined ( n :13; 26–35 weeks). Normal charts for components and volume flow were constructed ( n :72; 20–36 weeks) and related to data from growth restricted fetuses (birthweight < P5) ( n :20; 23–36 weeks). Results reproducibility CV was 5.4% (vessel area) and 7.3% (mean velocity) for scans and 6.6% and 10.5% for tracings resulting in a CV of 8.1% (scans) and 11.9% (tracings) for volume flow. Gestational age related increase exists for vessel area, mean flow velocity, and volume flow: 47.5 ± 19.3(SD) ml/min at 20 week and 229.6 ml/min ±29.6(SD) ml/min at 36 week, but not per kg/fetus. In fetal growth restriction, volume flow was reduced ( P < 5) in 18/20 cases, but for volume flow/kg fetus only in 11/20 cases. Conclusion Measurements of vessel area results in acceptable reproducibility of volume flow calculations, which show a 5‐fold increase at 20–36 week. In fetal growth restriction, volume flow is significantly reduced but equally distributed between normal and reduced values when calculated per kg/fetus.