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Multiple pregnancy
F41Early versus late multifetal pregnancy reduction, comparison of pregnancy outcome
Author(s) -
Jaffa A. J.,
HatToov J.,
Fait G.,
Wolman I.,
Gull I.,
Achiron R.,
Lipitz S.
Publication year - 2000
Publication title -
ultrasound in obstetrics and gynecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.202
H-Index - 141
eISSN - 1469-0705
pISSN - 0960-7692
DOI - 10.1046/j.1469-0705.2000.00015-1-41.x
Subject(s) - medicine , pregnancy , quadruplets , fetus , obstetrics , gestation , gestational age , gynecology , amniocentesis , group b , prenatal diagnosis , biology , genetics
Background To evaluate the pregnancy outcome of selective second‐trimester multifetal pregnancy reduction (MFPR) compared to late first‐trimester and early first‐trimester MFPR in triplets and quadruplets. Method The study groups comprised of 46, 47, and 48 patients who underwent MFPR at mean gestational of 11.2 (group A), 13.6 (group B), and 18.5 (group C) weeks, respectively. Patients of groups B and C underwent ultrasonographic fetal malformation screening. Some patients of group C had amniocentesis for chromosomal evaluation. Results No statistically significant difference was found between Group A, B, C regarding Pregnancy loss (4%, 4.3%, 2.5%, respectively), mean gestational age at delivery (35.8, 35.7, 35.8, respectively), and mean birth weight (2190, 2140, 2190, respectively). In group C fetal structural anomalies and chromosomal abnormalities were found in 4.2%, and 4.2% of pregnancies, respectively. Conclusion Pregnancy outcome was similar after MFPR at different stages of pregnancy. Selective second‐trimester MFPR is associated with favorable perinatal outcome and may facilitate detection of structural and chromosomal anomalies before the procedure and selective reduction of the affected fetus.