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F26Reproductive outcomes in women with arcuate and subseptate uteri
Author(s) -
Wölfer B.,
Lawrence A. C.,
Elson J.,
Jurkovic D.
Publication year - 2000
Publication title -
ultrasound in obstetrics and gynecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.202
H-Index - 141
eISSN - 1469-0705
pISSN - 0960-7692
DOI - 10.1046/j.1469-0705.2000.00015-1-26.x
Subject(s) - medicine , miscarriage , uterus , obstetrics , gynecology , pregnancy , infertility , fertility , uterine cavity , population , genetics , environmental health , biology
Background The effect of congenital uterine anomalies on reproductive performance is uncertain. The aim of this study to correlate uterine morphology with past reproductive outcomes in a large group of women with no history of infertility or recurrent pregnancy loss. Method In a period of three years 1028 women were recruited into the study. A detailed history of past pregnancies was obtained first, followed by transvaginal three‐dimensional ultrasound examination. The uterus was classified as being normal, arcuate or subseptate after the examination of uterine morphology in the coronal reformatted section. Uterine anomalies were classified according to the American Fertility Society classification and the degree of uterine cavity distortion was measured. Results 884 women had a normal uterus, 72 arcuate and 29 subseptate uteri. In the past they had total of 1944 pregnancies. The risk of miscarriage was significantly increased in both women with arcuate (OR = 1.9; 95% CI 1.1–3.5) and subseptate uteri (OR = 5.8; 95% CI 3.4–10.1) compared to those with normal uterine morphology. There was no correlation between the depth of uterine septum and the risk of miscarriage. Conclusion Miscarriage is significantly more frequent in women with arcuate and subseptate uterus. Further research is needed to assess potential benefits of surgical treatment in these cases.