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F02Sonographic preoperative assessment of myometrial invasion in endometrial cancer
Author(s) -
Exacoustòs C.,
Romanini M. E.,
Rinaldo D.,
Carusotti C.,
Arduini D.,
BenedettiPanici P.,
Romanini C.
Publication year - 2000
Publication title -
ultrasound in obstetrics and gynecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.202
H-Index - 141
eISSN - 1469-0705
pISSN - 0960-7692
DOI - 10.1046/j.1469-0705.2000.00015-1-2.x
Subject(s) - medicine , echogenicity , endometrial cancer , radiology , infiltration (hvac) , endometrium , stage (stratigraphy) , ultrasound , cancer , paleontology , physics , thermodynamics , biology
Background The purpose of this study was to assess the accuracy of transvaginal sonography (TVS) and Color/Power Doppler (CFD/PD) in evaluating the depth of myometrial invasion and preoperative staging of endometrial cancer. Method All patients (pts) with histological confirmed endometrial cancer were evaluated sonographically before surgery. In all patients the endometrium was scanned by TVS to evaluate thickness, echogenicity, border, intraluminal fluid and intracavitary masses. CFD/PD were used to evaluate vessels distribution and resistance indices: Myometrial infiltration was evaluated more or less than 50%. Sonographic results were compared to histological staging obtained after surgery. Results 53 patients were enrolled. All had endometrial thickness > 5 mm, mean thickness 19.5 ± 10.5 mm. Myometrial invasion was < 50% in 35 pts, TVS evaluation was exact in 33 cases, with a sensitivity of 94% and a positive predictive value (PPV) of 94%. An infiltration > 50% was seen with TVS in 12 pts and was histologically confirmed in 11, with a sensitivity of 82% and PPV of 75%. Other 3 pts had a cervical infiltration, 3 had stage 3, one had stage 4. TVS evaluated correctly 48 patients with a sensitivity of 91%. Conclusions TVS seems to be a valuable, noninvasive and unexpensive diagnostic method for the assessment of myometrial invasion.