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WS05‐4Assessment of uterine vascularity in endometrial cancer
Author(s) -
Szabó I.
Publication year - 2000
Publication title -
ultrasound in obstetrics and gynecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.202
H-Index - 141
eISSN - 1469-0705
pISSN - 0960-7692
DOI - 10.1046/j.1469-0705.2000.00009-1-33.x
Subject(s) - medicine , endometrial cancer , vascularity , grading (engineering) , uterine artery , blood flow , uterine cancer , stage (stratigraphy) , endometrium , gynecology , cancer , radiology , pregnancy , paleontology , gestation , civil engineering , genetics , biology , engineering
Background This study was conducted to assess uterine blood flow characteristics in endometrial cancer and to evaluate the influence of myometrial invasion and cancer grading for uterine circulation. Method Transvaginal color doppler was performed on 97 women with endometrial cancer (11 in stage IA, 33 in stage IB, 37 in stage IC, 7 in stage II, 8 in stage III, and 1 in stage IV) and 51 asymptomatic postmenopausal women (control group). Intratumoral and main uterine artery blood flow was recorded and the peak systolic velocity (PSV) and impedance indices (RI, PI) were calculated. Results In 90 of the 97 postmenopausal endometrial cancer patients (92%) abnormal blood flow with low impedance levels (RI: 0.39 ± 0.08; PI: 0.51 ± 0.15) was found within the endometrial echo or very close to it. Impedance indices in the main uterine arteries were significantly ( P < 0005) lower in women with endometrial cancer than in normal postmenopausal woman. Uterine blood flow was not modified by the cancer grading. There was, no difference in impedance indices of the uterine arteries between myometrial invasion of < 50% and > 50%. Conclusion These results suggest that uterine blood flow analysis in endometrial cancer could not predict the tumor staging and grading, but this examination can provide additional discriminatory information on tumor vascularity which can then be used with morphology for more accurate diagnosis.