Premium
WS02: Prenatal diagnosis
WS02‐01Sonographic measurement of fetal subcutaneous tissue of gestational diabetic mothers: a new criteria for therapy
Author(s) -
Ferrazzi E.,
Cetin I.,
Rigano S.,
Radaelli T.,
Taricco E.,
Bozzo M.,
Lanzani C.,
Pardi G.
Publication year - 2000
Publication title -
ultrasound in obstetrics and gynecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.202
H-Index - 141
eISSN - 1469-0705
pISSN - 0960-7692
DOI - 10.1046/j.1469-0705.2000.00009-1-10.x
Subject(s) - medicine , fetus , gestational diabetes , postprandial , gestational age , ultrasound , obstetrics , subcutaneous tissue , gestation , thigh , pregnancy , gynecology , insulin , surgery , radiology , genetics , biology
Objective The aim of this study was to compare sonographic measurements of subcutaneous tissue (SQ) in fetuses of gestational diabetic mothers (GDM), and in normal fetuses. Methods SQ was measured as the subcutaneous tissue area of mid upper arm (FMA), mid‐thigh (FMT) (cross sectional area minus bone and muscle area), abdominal (FA) and subscapular fat (FS), thickness. Fifty‐six GDM were enrolled in the study. Normal values were obtained from fetuses of normal pregnancies (BMI 21.3 ± 0.64 Kg/m 2 ; one hour glucose test < 140 mg/dL) (30 patients). Treatment was based on diet alone, or diet plus insulin according to postprandial glicemia. Longitudinal ultrasound examinations were performed every four weeks, in normal pregnancies, and in GDM pregnancies. Results Fetal SQ measurements were significantly correlated to gestational age both in normal and GDM fetuses ( P < 0.05). At the time of diagnosis GDM fetuses had significantly higher values for all SQ measurements compared to AGA fetuses; these differences were not found during therapy.26–32 weeks diagnosis 32–36 weeks therapynormal GDM normal GDM pFA 0.32 ± 0.01 0.38 ± 0.01 Ns 0.45 ± 0.02 0.47 ± 0.02 0.001 FS 0.28 ± 0.01 0.36 ± 0.17 Ns 0.41 ± 0.36 0.44 ± 0.02 0.001 FMA 1.97 ± 0.12 2.55 ± 0.19 Ns 3.83 ± 0.33 4.24 ± 0.21 0.01 FMT 3.12 ± 0.20 4.10 ± 0.37 Ns 5.91 ± 0.42 6.94 ± 0.43 0.01Conclusions GDM is associated with increases in fetal SQ from the second trimester. A strict glycemic control can reduce these differences to negligible values. These new measurements can be adopted to monitor the efficacy of therapy in GDM pregnancies.