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P99Effect of the vitamin E on the vasoconstrictor reflex
Author(s) -
López Ramón y Cajal C.
Publication year - 2000
Publication title -
ultrasound in obstetrics and gynecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.202
H-Index - 141
eISSN - 1469-0705
pISSN - 0960-7692
DOI - 10.1046/j.1469-0705.2000.00004-1-98.x
Subject(s) - medicine , vitamin e , fetus , endocrinology , antioxidant , biochemistry , pregnancy , chemistry , biology , genetics
Background The vitamin E is an antioxidant agent used in the regulation of the vascular reactivity. We describe the use of the vitamin E on the regulation of the vasoconstrictor effect (VE) of the proximal segment of the middle cerebral artery (pMCA). Method In 11 fetuses we performed a pressure test . First the VE was demonstrated using pulsed Doppler and then we administrate orally vitamin E to the pregnant (15–50 mg per day). Later, we repeat the pt to observe the response on the VE. Results After the vitamin E the VE was decreased or abolished (see table at top of page).Number
of caseW/VE/E
(mg)W/VE/E
(mg)W/VE/E
(mg)W/VE/E
(mg)1 30 5 /++/start 15 30 6 /+/15 34/0/15 36/0/15 2 30 5 /+/start 15 33 4 /+I/15 34/0/15 37/0/15 3 33 2 /++I/start 15 34 2 /0/15 35 2 /0/15 36/0/15 4 30 6 /++/start 15 31 6 /0/15 35/0/155 29 2 /++I/start 50 31 2 /0/506 31 3 /++I/start 50 33/0/50 35 5 /0/507 25 6 /++/start 50 26 3 /0/508 29 3 /++I/start 50 29 6 /0/509 29 3 /++/start 50 29 6 /++I/100 30 2 /+/0/50 31 1 /0/50 10 26 5 /++I/start 50 27 2 /0/5011 28 2 /++I/start 50 29/0/50W = weeks. E = vitamin E. + = ve; 0 = no ve. i = inverse flow in the pMCA.Conclusion With vitamin E we can regulate the VE of the pMCA. This response could avoid some perinatal motor injury of intrauterine origin and best the neonatal vascular adaptation.