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P09Flow velocity waveforms in the spiral artery versus AFP and BHCG maternal serum concentration in pregnancy complicated by threatened abortion
Author(s) -
PersonaSliwiñska A.,
Brazert J.,
Biczysko R.
Publication year - 2000
Publication title -
ultrasound in obstetrics and gynecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.202
H-Index - 141
eISSN - 1469-0705
pISSN - 0960-7692
DOI - 10.1046/j.1469-0705.2000.00004-1-9.x
Subject(s) - medicine , threatened abortion , spiral artery , blood flow , pregnancy , spiral (railway) , obstetrics , fetus , early pregnancy factor , ultrasound , abortion , cardiology , placenta , gestation , radiology , mathematical analysis , genetics , mathematics , biology
Objectives The aim of the study was to determine the values of resistance index (RI) and pulsatility index (PI) in the spiral arteries and to evaluate the maternal serum concentration of AFP and β‐hCG trying to find correlation between these parameters in the patients in early pregnancy complicated by threatened abortion. Study methods We have analysed 32 pregnant women between 5th and 12th weeks of pregnancy diagnosed as threatened abortion. In all patients TV ultrasound with pulsed color doppler was performed. The RI and PI were calculated for blood flow obtained from the spiral arteries. The concentration of AFP and β‐hCG in maternal serum was evaluated by immunoassays. Results 32 velocity waveforms from spiral arteries were analysed and blood flow indices were calculated. We have found statistically significant negative correlation between the values of both blood flow parameters (RI & PI) and successive weeks of pregnancy. In the tested group in 37.5% of patients the level of β‐hCG was low. There was statistically significant correlation between serum β‐hCG, AFP concentrations and blood flow parameters. Conclusions Only the combination of Doppler blood flow analysis in spiral arteries and evaluation of AFP and β‐hCG in the maternal serum performed in first trimester may be useful for the intensive fetal monitoring of high risk pregnancies.