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P49Prenatal diagnosis of myelocystocele‐cloacal exstrophy in a male neonate with a abnormal penis and urethra
Author(s) -
De León J. A,
Pintado P.,
Viñuela M.,
Herrero E.,
García F.,
Aguarón A.,
Pérez Fernández R.
Publication year - 2000
Publication title -
ultrasound in obstetrics and gynecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.202
H-Index - 141
eISSN - 1469-0705
pISSN - 0960-7692
DOI - 10.1046/j.1469-0705.2000.00004-1-49.x
Subject(s) - cloacal exstrophy , cloaca , medicine , anatomy , omphalocele , pouch , genitourinary system , abdominal wall , urethra , craniofacial , abdominal wall defect , penis , surgery , bladder exstrophy , fetus , pregnancy , biology , genetics , psychiatry
Cloacal exstrophy results from a migration failure of the lateral mesodermal folds of the infraumbilical anterior abdominal wall, and rupture of the resulting enlarged, persistent cloacal membrane before the eighth week of gestation. Myelocystocele is a defect of the medular channel characterizased by a cystic that contain dural and arachnoid layer and the ependymal lining layer, respectively. The association of persistent cloaca and caudal spinal anomalies is thought to be related to cell loss in the caudal cell mass, which affects caudal spinal column formation and cleavage of the cloaca by the urorectal septum. Cloacal malformation occurs in approximately 1 in 65 000 live male births. Prenatal ultrasound may lead to the diagnosis in selected cases. Case report We report an unusual case of prenatally detected with a myelocystocele and cloacal malformation. Additional anomalies included an omphalocele and malformations of the upper urogenital tract, skeleton, and vertebral column. Labor was induced at 34 weeks' estimated gestational age. It finish by eutocical delivery. A 2154‐g male was born, Apgar 6/8, pH 7.32. The newborn was taken to NCIU and the neonatal outcome was favourable.