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P48Parameters of renal function by the obtention of fetal urine by intrauterine aspiration
Author(s) -
Troyano Luque J. M.,
Clavijo M. T.,
Feo C. M.,
Laynez E.,
Gómez M.
Publication year - 2000
Publication title -
ultrasound in obstetrics and gynecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.202
H-Index - 141
eISSN - 1469-0705
pISSN - 0960-7692
DOI - 10.1046/j.1469-0705.2000.00004-1-48.x
Subject(s) - medicine , uric acid , renal function , endocrinology , fetus , diuresis , excretion , kidney , urology , pregnancy , genetics , biology
Background We have studied the fetal renal function by urinary biochimical analysis obtained by aspirative nephrostomy. Method Since 1993 we have practiced in our ultrsound unite 51 aspirative nephrostomies in cases of over 15 mm hydronephrosis since the 20th week of pregnancy. We have determined the tubular dynamic of Na + , Cl − , K + , P + , the excretory response after overcharge of the NaCl, the tubular response to the aqueous diuresis, Calcium tubular dynamic, uric acid, glucose. Acid‐base equilibrium. Results Limited excretory capacity of Na + and Cl − . Excretory diminishing with Na + Cl − overcharge. The diuresis aqueous decreases the reabsortion of Na + , Cl − , Ca + , P + , glucose and uric acid. In premature fetuses there is hypocalciuria with hyperphosphaturia. The excretion of uric acid is higher in premature fetuses (7.7 ± 2.7 mg/dl) than in mature fetuses (5.2 ± 1.6 mg/dl). The excretion of glucose is higher in premature fetuses. In all the cases a perinatal renal function was verifyed. In a 78.4% of the cases, reparatory surgery was needed. Dyalisis wasn't needed in any new‐born. In two of the cases unilateral nephrectomy was needed. Conclusion The theoretical renal obstructive prenatal problems are not always associated to renal disfunction. The neprhourological matureness presents important changes in tubular dynamic of Ca + , P + , glucose and uric acid, nevertheless it keeps the same tubular dynamic with Na + , Cl − and potassium.