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P119Usefulness fetal echocardiography in the prenatal diagnosis of Down Syndrome (analysis of the 40 cases)
Author(s) -
Krasoń A.,
Kaczmarek P.,
Janiak K.,
Piotrowicz M.,
Nowicki G.,
RespondekLiberska M.
Publication year - 2000
Publication title -
ultrasound in obstetrics and gynecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.202
H-Index - 141
eISSN - 1469-0705
pISSN - 0960-7692
DOI - 10.1046/j.1469-0705.2000.00004-1-118.x
Subject(s) - medicine , pericardial effusion , fetal echocardiography , down syndrome , hydrops fetalis , trisomy , fetus , prenatal diagnosis , polyhydramnios , atresia , cardiology , heart disease , pregnancy , psychiatry , biology , genetics
Background The aim of our study was retrospective analysis of 40 cases fetuses with down syndrome (T21) who had detailed sonography and echocardiography. Method Video tape analysis of 40 fetuses with T21 who had completed ultrasound and echocardiography examinations and completed neonatal follow‐up in the same center. Results In our study the majority of cases 26 (65%) were low risk pregnancies. High risk pregnancies were in 14 (35%) cases. Congenital heart defect (72%) (AV‐canal in 13/18 cases) was the most common anomaly diagnosed prenataly in fetuses with T21. Functional cardiac anomalies with normal heart anatomy were recorded also such as: dyspoportion and hypertrophy in 4/12 cases, tricuspid valve regurgitation, bright spot and pericardial effusion in 3/12 cases. Extracardiac malformations (25%) were diagnosed in fetuses with T21 such as: dudenal atresia, femur length shortening, pyelectasis bilateralis, face anomalies, sceletal malformations, hydrops fetalis. Conclusions 1. Congenital heart defect (72%) (AV‐canal in 13/18 cases) was the most common anomaly diagnosed in fetuses with T21. 2. The most common extracardiac malformation was duodenal atresia 13/40 = 32.5% cases. 3. Fetal echocardiography can be usefull to identify in the group of low risk pregnancies, the potential patients for cytogenetic examinations of trisomy 21.