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109Transcranial‐duplex‐Doppler US findings and neurodevelopmental outcome of infants with perinatal cerebral infarction
Author(s) -
Ðuranović V.,
MejaškiBošnjak V.,
MarušićDella Marina B.,
Duplanćić R.,
Lujić L.,
BabicPolak J.,
Huzjan R.
Publication year - 2000
Publication title -
ultrasound in obstetrics and gynecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.202
H-Index - 141
eISSN - 1469-0705
pISSN - 0960-7692
DOI - 10.1046/j.1469-0705.2000.00004-1-108.x
Subject(s) - medicine , lesion , etiology , hemiparesis , middle cerebral artery , infarction , cerebral blood flow , pediatrics , cerebral infarction , cerebral arteries , cardiology , radiology , surgery , ischemia , myocardial infarction
Objectives We recorded cerebral flow velocities by TCDD in 10 infants diagnosed with cerebral infarction (CI) of the irrigational area of the middle cerebral artery (MCA), with special reference to the etiology and pathogenesis of CI. We correlated the hemispheral localization and the distribution of the lesion with neurodevelopmental outcome of the children affected. Patients and methods Two children were preterms and other eight were full terms. The diagnosis was obtained in all children by using cranial US, CT and MRI. Because of vascular etiology of lesion cerebral circulation was investigated by TCDD. Perinatal risk factors were assessed and patients underwent neurodevelopmental follow‐up for 1–14 years. Results Cerebral infarction involved the irrigational area of MCA. Asymmetric flow between the left and right MCA was the main finding on the TCDD. Lower velocities were found in the MCA on the affected side. These side‐to‐side differences were present at subsequent Doppler measurements. The lesion was more often found on left size. The distribution of the infarction was classified as the area of the lesion determines the neurological sequels. All infants had delayed psychomotoric development: contralateral hemiparesis, persistent seizures and language delay. The level of cognitive functioning was variable. Conclusions Based on clinical and diagnostical follow‐up the results showed no simple and clear connection between lesion parameters and neurodevelopmental outcome. We suppose that the time when lesion occurred is crucial for the possible neurodevelopmental outcome. The data indicates that beside brain US, CT and MR, TCDD can be useful method for identifying and following infants with suspected cerebral infarction.