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Hysteroscopy provides proof of trophoblastic tumors in three cases with negative color Doppler images
Author(s) -
Lindholm H.,
Rådestad A.,
Flam F.
Publication year - 1997
Publication title -
ultrasound in obstetrics and gynecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.202
H-Index - 141
eISSN - 1469-0705
pISSN - 0960-7692
DOI - 10.1046/j.1469-0705.1997.09010059.x
Subject(s) - medicine , gestational trophoblastic disease , trophoblastic tumor , hysteroscopy , color doppler , placental site trophoblastic tumor , human chorionic gonadotropin , trophoblastic neoplasm , radiology , chorioepithelioma , uterus , partial hydatidiform mole , pregnancy , gynecology , pathology , placenta , choriocarcinoma , gestation , fetus , hormone , ultrasonography , genetics , biology
Color Doppler sonography has replaced pelvic arteriography as well as real‐time ultrasound in the assessment of patients with gestational trophoblastic disease. In about 25% of patients in whom human chorionic gonadotropin (hCG) levels are suggestive of trophoblastic disease, there will be no evidence of abnormal vessels in the uterus. In these cases it is assumed that hCG was produced by metastatic lesions. We present here three cases in which color Doppler examination was negative and where myometrial biopsies containing tumor were obtained by means of hysteroscopy. The fact that color Doppler, in its present form, does not detect small areas of trophoblastic tumor might also have implications for other kinds of tumors. Knowledge of the exact microscopic diagnosis in molar patients with persistent disease may have an impact on management. Copyright © 1997 International Society of Ultrasound in Obstetrics and Gynecology