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Relationship between umbilical and fetal cerebral blood flow velocity waveforms and umbilical venous blood gases
Author(s) -
Bonnin Ph.,
Guyot B.,
Bailliart O.,
Benard C.,
Blot Ph.,
Martineaud J. P.
Publication year - 1992
Publication title -
ultrasound in obstetrics and gynecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.202
H-Index - 141
eISSN - 1469-0705
pISSN - 0960-7692
DOI - 10.1046/j.1469-0705.1992.02010018.x
Subject(s) - medicine , umbilical vein , fetus , venous blood , blood flow , cerebral blood flow , umbilical cord , obstetrics , cardiology , anesthesia , pregnancy , anatomy , biochemistry , chemistry , biology , in vitro , genetics
Nineteen women (mean ± SD: 28 ± 5 years) with small fetuses relative to gestational age (mean ± SD: 32 ± 2.2 weeks of gestation) were referred to our unit for cordocentesis for the determination of fetal karyotyping. Four of these 19 patients had small‐for‐gestational‐age ultrasound‐derived measurements under the third centile for gestational age. Fetal blood gases were measured in the umbilical vein. Umbilical artery and fetal internal carotid artery Doppler examinations were performed 15 min before cordocentesis. The results showed a progressive and proportional increase in umbilical artery resistance index with hypoxia ( p < 0.001), hypercapnia ( p < 0.025) and acidosis ( p < 0.005). Moreover, the results showed a progressive and proportional decrease in fetal internal carotid artery resistance index with hypoxia ( p < 0.01), hypercapnia ( p < 0.01) and acidosis ( p < 0.025). Fetal blood gases are therefore related to umbilical circulatory function and cerebral vasodilatation, suggesting fetal vascular redistribution. Copyright © 1992 International Society of Ultrasound in Obstetrics and Gynecology