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Elastosis perforans serpiginosa in an adult with Down's syndrome: report of a case with symmetrical localized involvement
Author(s) -
De Pasquale R,
Nasca MR,
Musumeci ML,
Micali G
Publication year - 2002
Publication title -
journal of the european academy of dermatology and venereology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.655
H-Index - 107
eISSN - 1468-3083
pISSN - 0926-9959
DOI - 10.1046/j.1468-3083.2002.00541.x
Subject(s) - medicine , dermatology
Elastosis perforans serpiginosa (EPS) is a rare perforating dermatosis in which elastic fibers extrude from the papillary dermis producing umbilicated papules, characteristically arranged to form arciform or serpiginous patterns on the skin. It can be observed in patients with Down's syndrome, in whom in some cases the disease has been reported to be more widespread and to run a longer course. We present the case of a 20‐year‐old girl with Down's syndrome, hypothyroidism, acne and hypertrichosis, who had a 2‐year history of multiple atrophic lesions with an arciform pattern on the distal extensor portions of both thighs, histologically showing the typical features of EPS.