Premium
Mycosis fungoides presenting as Ofuji's papuloerythroderma
Author(s) -
Hur J,
Seong JY,
Choi TS,
Jang JG,
Jang MS,
Suh KS,
Kim ST
Publication year - 2002
Publication title -
journal of the european academy of dermatology and venereology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.655
H-Index - 107
eISSN - 1468-3083
pISSN - 0926-9959
DOI - 10.1046/j.1468-3083.2002.00486.x
Subject(s) - mycosis fungoides , medicine , dermatology , erythema , peripheral t cell lymphoma , pathology , gene rearrangement , t cell , immunology , lymphoma , gene , immune system , biology , biochemistry
We report three patients presented with clinical features of Ofuji's papuloerythroderma (pruritic erythematous papules and extensive erythema sparing all skin folds), however, showing histopathological findings of mycosis fungoides (Pautrier's microabscess, haloed lymphocytes, disproportionate epidermotropism, and wiry collagen bundles). One case was associated with plaque stage of mycosis fungoides and follicular mucinosis. T‐cell receptor (TCR) gene rearrangement analysis in the lesional skin tissue demonstrated rearrangement of the gamma chain in all cases. HTLV‐1 serology was negative for two patients who conducted HTLV‐1 test. We think that Ofuji's papuloerythroderma might be a variant of early mycosis fungoides rather than secondary skin manifestations to certain cutaneous inflammatory diseases.