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Treatment of chronic radiation ulcers with recombinant platelet‐derived growth factor and a hydrophilic copolymer membrane
Author(s) -
Wollina U,
Liebold K,
Konrad H
Publication year - 2001
Publication title -
journal of the european academy of dermatology and venereology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.655
H-Index - 107
eISSN - 1468-3083
pISSN - 0926-9959
DOI - 10.1046/j.1468-3083.2001.00348.x
Subject(s) - medicine , mycosis fungoides , copolymer , dermatology , growth factor , lymphoma , platelet , membrane , radiodermatitis , irradiation , radiation therapy , surgery , pathology , biochemistry , physics , receptor , nuclear physics , polymer , chemistry , organic chemistry
We report on a 59‐year‐old woman suffering from cutaneous T‐cell lymphoma of the mycosis fungoides type, who developed chronic ulcerating radiation dermatitis after total body electron beam irradiation with a cumulative dose of 36 Gy. The painful and easily bleeding ulcers could be markedly improved using a combined approach with topical platelet‐derived growth factor gel and hydrophilic copolymer membranes.