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Bath psoralen‐ultraviolet A therapy in atopic eczema
Author(s) -
De Kort Wja,
Van Weelden H
Publication year - 2000
Publication title -
journal of the european academy of dermatology and venereology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.655
H-Index - 107
eISSN - 1468-3083
pISSN - 0926-9959
DOI - 10.1046/j.1468-3083.2000.00067.x
Subject(s) - medicine , psoralen , itching , atopic dermatitis , dermatology , puva therapy , ultraviolet a , ultraviolet therapy , psoriasis , dna , genetics , biology
Aims To evaluate the efficacy of bath psoralen‐ultraviolet A (PUVA) therapy in severe cases of atopic dermatitis (AD) in adults using the extended Six Area, Six Sign Atopic Dermatitis (SASSAD) score. Methods Thirty‐five adult subjects with severe AD underwent bath PUVA therapy for a maximum of 30 sessions ranging from one to three times a week. The only other treatment allowed during the study was topical application of hydrocortisone. Results There were a total of six drop‐outs, three due to aggravation of symptoms. After the maximum 30 sessions the remaining 29 subjects showed 82.1% improvement in the severity of lesions, 75.2% reduction in extension of lesions, 74% improvement in itching and 79% improvement in night‐time rest. Patient evaluations gave an overall score of 8.8 on a scale of 0–10.