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SCA2 and SCA3 mutations in young‐onset dopa‐responsive parkinsonism
Author(s) -
Svetel M.,
Djarmati A.,
Dragašević N.,
Savić D.,
Čuljković B.,
Romac S.,
Kostić V. S.
Publication year - 2003
Publication title -
european journal of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.881
H-Index - 124
eISSN - 1468-1331
pISSN - 1351-5101
DOI - 10.1046/j.1468-1331.2003.00671.x
Subject(s) - spinocerebellar ataxia , parkinsonism , medicine , mutation , genetics , disease , degenerative disease , gene , biology
In this study no one of our 85 patients of Serbian origin with young‐onset (≤ 45 years) dopa‐responsive parkinsonism (YOP), previously proved negative for PARK1 and PARK2 mutations, had either spinocerebellar ataxia type 2 (SCA2) or SCA3 mutation. These data do not prove the significance of these two mutations in either sporadic or familial YOP suggestive of Parkinson's disease.