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Predicting spontaneous early neurological recovery after acute ischemic stroke
Author(s) -
Arboix Adrià,
GarcíaEroles Lluis,
Comes Emili,
Oliveres Montserrat,
Balcells Miquel,
Pacheco Gustavo,
Targa Cecilia
Publication year - 2003
Publication title -
european journal of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.881
H-Index - 124
eISSN - 1468-1331
pISSN - 1351-5101
DOI - 10.1046/j.1468-1331.2003.00630.x
Subject(s) - medicine , dysarthria , modified rankin scale , stroke (engine) , logistic regression , odds ratio , infarction , multivariate analysis , cerebral infarction , cohort , ischemic stroke , pediatrics , cardiology , ischemia , myocardial infarction , audiology , mechanical engineering , engineering
We assessed predictors of spontaneous early neurological recovery after acute ischemic stroke by means of multivariate analysis in a cohort of 1473 consecutive patients treated at one academic center. At hospital discharge, spontaneous neurological improvement or good outcome was defined as grades 0–2 of the Rankin scale, and poor outcome (no improvement or in‐hospital death) as grades 3–5. Spontaneous recovery of neurological deficit at the time of discharge from the hospital was observed in 16% of patients with cerebral infarction ( n = 238). Dysarthria‐clumsy hand syndrome improved in 44% of patients and was the only variable significantly associated with in‐hospital functional recovery in three logistic regression models that in addition to lacunar syndromes, included demographic variables, cardiovascular risk factors, and clinical variables [odds ratio (OR) 2.56], neuroimaging findings (OR 2.48), and outcome data (OR 2.39), respectively. Clinical factors related to severity of infarction available at stroke onset have a predominant influence upon in‐hospital outcome and may help clinicians to assess prognosis more accurately. Our work gives a contribution into prognostic factors after acute ischemic stroke. With regard to patterns of stroke, dysarthria‐clumsy hand syndrome was a significant predictor of spontaneous in‐hospital recovery in ischemic stroke patients.