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Striatal infarcts mimicking frontotemporal dementia: a case report
Author(s) -
Nishio Y.,
Nakano Y.,
Matsumoto K.,
Hashimoto M.,
Kazui H.,
Hirono N.,
Ishii K.,
Mori E.
Publication year - 2003
Publication title -
european journal of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.881
H-Index - 124
eISSN - 1468-1331
pISSN - 1351-5101
DOI - 10.1046/j.1468-1331.2003.00628.x
Subject(s) - frontotemporal dementia , basal ganglia , striatum , medicine , neuroscience , thalamus , dementia , pathology , positron emission tomography , disease , psychology , central nervous system , dopamine
We described a patient with bilateral striatal infarcts, in whom stereotyped and disinhibited behaviors were insidiously emerged over 2 years mimicking frontotemporal dementia (FTD). A positron emission tomography with 18‐fluorodeoxy glucose showed a hypometabolism in the frontal lobes, basal ganglia, and thalami. The peculiar behavioral alterations remained unchanged for the following 7 years, suggesting that the disease is not degenerative but of vascular origin. A disruption of the fronto‐subcortical circuits at the level of the striatum or the anterior thalamic peduncle is attributable to the FTD‐like behavioral and cognitive syndrome.