Premium
Evidence of an association between Chlamydia pneumoniae and cerebrovascular accidents
Author(s) -
Bucurescu G.,
Stieritz D. D.
Publication year - 2003
Publication title -
european journal of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.881
H-Index - 124
eISSN - 1468-1331
pISSN - 1351-5101
DOI - 10.1046/j.1468-1331.2003.00605.x
Subject(s) - medicine , chlamydia , stroke (engine) , diabetes mellitus , chlamydiales , antibody , chlamydiaceae , thrombosis , immunology , endocrinology , mechanical engineering , engineering
The authors report results of a retrospective pilot study showing a strong association between patients with stroke/TIA and the presence of circulating IgG and IgA antibodies to Chlamydia pneumoniae. These results support the hypothesis that chronic active or persistent infection may play a role in the mechanism of thrombosis. The risk for stroke associated with Chlamydial circulating antibodies appeared to be independent of other risk factors such as diabetes and hypercholesterolemia.