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Mycophenolate in treatment‐resistant inflammatory neuropathies
Author(s) -
Umapathi T.,
Hughes R.
Publication year - 2002
Publication title -
european journal of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.881
H-Index - 124
eISSN - 1468-1331
pISSN - 1351-5101
DOI - 10.1046/j.1468-1331.2002.00478.x
Subject(s) - medicine , mycophenolate , polyradiculoneuropathy , multifocal motor neuropathy , drug , corticosteroid , chronic inflammatory demyelinating polyneuropathy , dermatology , pharmacology , guillain barre syndrome , immunology , transplantation , mismatch negativity , electroencephalography , psychiatry , antibody
There has been an increasing interest in the use of mycophenolate as an immunomodulatory drug in neuromuscular diseases. We report five consecutive patients with treatment‐resistant chronic inflammatory demyelinating polyradiculoneuropathy or multifocal motor neuropathy who were treated with mycophenolate. None showed clinically significant benefit. The use of mycophenolate did not result in the reduction in the dose of corticosteroid or other immunosuppressive agents in any patient. Side‐effects, although not serious, were troubling enough for two patients to stop mycophenolate.