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Paroxysmal kinesigenic choreoathetosis because of cryptogenic myelitis. Remission with carbamazepine and the pathogenetic role of altered sodium channels
Author(s) -
Bonev V. I.,
Gledhill R. F.
Publication year - 2002
Publication title -
european journal of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.881
H-Index - 124
eISSN - 1468-1331
pISSN - 1351-5101
DOI - 10.1046/j.1468-1331.2002.00440.x
Subject(s) - medicine , choreoathetosis , carbamazepine , paroxysmal dyskinesia , myelitis , etiology , multiple sclerosis , pediatrics , spinal cord , anesthesia , epilepsy , pathology , dyskinesia , immunology , psychiatry , dystonia , disease , parkinson's disease
Lesions of the spinal cord causing paroxysmal kinesigenic choreoathetosis are rare and most of the reported cases have been because of multiple sclerosis. We now describe this movement disorder occurring in a patient who developed a myelitis of unknown aetiology. A typically striking remission followed treatment with carbamazepine. It is suggested that the effect of the drug and the disorder itself may both be explained on the basis of altered sodium channels.