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Paroxysmal dystonia induced by exercise and acetazolamide
Author(s) -
Guimarães J.,
Vale Santos J.
Publication year - 2000
Publication title -
european journal of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.881
H-Index - 124
eISSN - 1468-1331
pISSN - 1351-5101
DOI - 10.1046/j.1468-1331.2000.00049.x
Subject(s) - acetazolamide , medicine , dystonia , gabapentin , anesthesia , magnetic resonance imaging , electroencephalography , psychiatry , radiology , pathology , alternative medicine
We report a case of a 40‐year‐old woman with dystonic attacks precipitated by slight exercise. Episodes lasted 2–5 min and were not precipitated by sudden movements or by being startled, drinking alcohol, coffee or tea, or by stress. Secondary dystonia was ruled out and brain magnetic resonance imaging (MRI) was unremarkable. Routine and video electroencephalogram (EEG) during and between attacks were normal. Acetazolamide greatly worsened her condition, whereas gabapentin [1‐(aminomethyl) cyclohexaneacetic acid] treatment markedly reduced the frequency and severity of the episodes.