Premium
Type 2 diabetes mellitus: a disease of the innate immune system? An update
Author(s) -
Crook M.
Publication year - 2004
Publication title -
diabetic medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.474
H-Index - 145
eISSN - 1464-5491
pISSN - 0742-3071
DOI - 10.1046/j.1464-5491.2003.01030.x
Subject(s) - medicine , innate immune system , diabetes mellitus , type 2 diabetes mellitus , immune system , disease , macrovascular disease , acute phase protein , immunology , type 2 diabetes , endocrinology , inflammation
A few years ago a hypothesis was proposed suggesting that elements of the innate immune system, such as acute phase reactants, contribute to the development of Type 2 diabetes mellitus. Acute phase reactants such as C‐reactive protein and sialic acid may thus predict risk of developing Type 2 diabetes mellitus, as well as being markers of diabetes microvascular and macrovascular complications. This article discusses these issues.