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Use of oral fluorescein angiography in the diagnosis of macular oedema within a diabetic retinopathy screening programme
Author(s) -
Razvi F. M.,
Kritzinger E. E.,
Tsaloumas M. D.,
Ryder R. E. J.
Publication year - 2001
Publication title -
diabetic medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.474
H-Index - 145
eISSN - 1464-5491
pISSN - 0742-3071
DOI - 10.1046/j.1464-5491.2001.00633.x
Subject(s) - medicine , fluorescein angiography , diabetic retinopathy , fluorescein , ophthalmology , retinopathy , gold standard (test) , angiography , diabetes mellitus , eye disease , surgery , radiology , visual acuity , fluorescence , physics , quantum mechanics , endocrinology
Aims To assess if oral fluorescein angiography (OFA) is a suitable screening method to detect macular oedema in diabetic retinopathy. Methods Eighty‐four diabetic patients were included in the study. They were from a consecutive series of patients attending the diabetic eye‐screening clinic, with retinopathy at the macula requiring ophthalmology assessment. All patients were subsequently examined in the eye hospital, by ophthalmologist slit lamp biomicroscopy assessment as the gold standard, followed by oral fluorescein angiography. Results This study indicates a sensitivity of 92% and specificity of 81%. Only 4.8% of patients developed a minor reaction to oral fluorescein; 84.5% of images were of good quality. Conclusions Oral fluorescein angiography is an efficient and highly sensitive tool for the detection of macular oedema. It can be used as an adjunct in the diabetic screening service to identify patients with oedema within a disc diameter of the macula. Ultimately it will ensure that only necessary and smaller numbers of patients are referred to ophthalmologists. Diabet. Med. 18, 1003–1006 (2001)