Premium
Clinical scenario
Author(s) -
WILLIAM E. CAYLEY
Publication year - 2001
Publication title -
diabetic medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.474
H-Index - 145
eISSN - 1464-5491
pISSN - 0742-3071
DOI - 10.1046/j.1464-5491.2001.00001-4.x
Subject(s) - medicine , citation , information retrieval , library science , computer science
Both study designs were randomized, double-blind, placebo-controlled trials qualifying as a level of evidence Ia. In the study by Martinez, Franceschini, Patta, Quintana, Gomes, et al. (2009), half of the women received a single dose of tinidazole (2g) in addition to 2 placebo capsules while half received tinidazole (2g) supplemented with 2 capsules containing L. rhamnosus GR-1 and L. reuteri RC-14. Martinez, Franceschini, Patta, Quintana, Candido, et al. (2009) administered fluconazole (150 mg) with 2 oral capsules of L. rhamnosus GR-1 and L. reuteri RC-14 to 29 subjects while 26 subjects were treated with fluconazole and placebo capsules. The medication regimens in both trials were taken every morning for 28 days starting on the day of “azole” antifungal use.