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Diabetes mellitus secondary to glycogen storage disease type III
Author(s) -
Oki Y.,
Okubo M.,
Tanaka S.,
Nakanishi K.,
Kobayashi T.,
Murase T.
Publication year - 2000
Publication title -
diabetic medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.474
H-Index - 145
eISSN - 1464-5491
pISSN - 0742-3071
DOI - 10.1046/j.1464-5491.2000.00378.x
Subject(s) - medicine , glycogen storage disease , diabetes mellitus , type 2 diabetes mellitus , glycogen storage disease type i , disease , endocrinology
SUMMARYBackground Diabetes mellitus is a rare complication of glycogen storage disease type III (GSD III). Case report We describe a 47‐year‐old man with GSD III who developed diabetes mellitus. He was diagnosed as having GSD III at the age of 18 years, and his glucose tolerance was normal at that time. Liver dysfunction and muscle atrophy gradually progressed, and the patient developed diabetes mellitus at the age of 45. When the post‐prandial hyperglycaemia worsened, we instituted treatment with an alpha‐glucosidase inhibitor, voglibose, and this improved glycaemic control without any adverse effects. Conclusions We recommend serial evaluation for complications of GSD III, and propose that an alpha‐glucosidase inhibitor may be a favourable drug in treating diabetes mellitus secondary to GSD III.