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Author(s) -
Heller, S.,
Amiel, S.,
Beveridge, S.,
Bradley, C.,
Gianfrancesco, C.,
James, P.,
McKeown, N.,
Newton, D.P.,
Newton, L.P.,
Oliver, L.,
Reid, H.,
Roberts, H.,
Robson, S.,
Rollingson, J.,
Scott, V.,
Speight, J.,
Taylor, C.,
Thompson, G.,
Wright, F.
Publication year - 2002
Publication title -
diabetic medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.474
H-Index - 145
eISSN - 1464-5491
pISSN - 0742-3071
DOI - 10.1046/j.1464-5491.19.s2.6.x
Subject(s) - medicine , citation , information retrieval , library science , computer science
Results: HbA1c improved 6 months after training (ID and DD) and was partially maintained at one year (ID) (F=57.2,p<0.0001) (mean±SEM): 6 months: -1.0±0.1%,p<0.0001; 12 months: -0.5±0.2%,p=0.001). ADDQoL scores showed a similar pattern of improvement (e.g. dietary freedom item: F=54.6,p<0.0001), fully maintained at 1 year as were DTSQ (F=125.9,p<0.0001) and W-BQ12 (F=40.3,p<0.0001). Severe hypoglycaemia, weight and lipids remained unchanged. Conclusion: The principles of intensive flexible insulin therapy with an unrestricted diet translate well to people with Type 1 diabetes in the UK, resulting in improved glycaemic control and quality of life and should be more generally available.