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A comparison of the histopathological findings after open and percutaneous needle testicular biopsy in adult male rats
Author(s) -
Altay B.,
Hekimgil M.,
Kefi A.,
Girgin C.,
Çikili N.
Publication year - 2000
Publication title -
bju international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 1464-4096
DOI - 10.1046/j.1464-410x.2000.00935.x
Subject(s) - biopsy , medicine , percutaneous , open biopsy , urology , surgery , radiology
Objective To define the histopathological changes occurring as a result of open and percutaneous needle testicular biopsy in adult rats. Materials and methods Percutaneous needle and open testicular biopsies were taken from 35 male albino rats (120–140 days old). Nine of the rats were killed 10 days after the biopsy, eight after 30 days and the other eight 60 days after the biopsy. A control group of six rats underwent orchidectomy with no preceding testicular biopsy. Results Significant tubulitis and obstructive findings were detected 10 days after needle biopsy ( P < 0.05); epididymo‐orchitis was frequent after open biopsy during this period. At 10–30 days after needle biopsy the mean seminiferous tubule diameters were significantly greater than in either the control group or after open biopsy ( P < 0.05). The histopathological damage recovered 60 days after open and needle biopsy. Conclusion Although percutaneous, a needle biopsy (as an alternative to open biopsy) causes tubulitis and frequent obstructive findings in the early period; therefore, repeat testicular procedures should be planned after these changes have resolved.