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Five‐year data from the Oxford Laser Prostatectomy Trial
Author(s) -
Keoghane S.R.,
Sullivan M.E.,
Doll H.A.,
Kourambas J.,
Cranston D.W.
Publication year - 2000
Publication title -
bju international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 1464-4096
DOI - 10.1046/j.1464-410x.2000.00778.x
Subject(s) - medicine , prostatectomy , transurethral resection of the prostate , randomized controlled trial , natural history , surgery , urology , prostate , cancer
Objective To evaluate the natural history of a group of patients who underwent contact laser prostatectomy or transurethral resection of the prostate (TURP). Patients and methods Patients were followed up at 5 years after enrolling in a prospective double‐blind randomized controlled trial of TURP vs contact laser prostatectomy. Results Of the initial trial patients, 11.5% had died (seven in the laser and 10 in the TURP arm) and eight (5.4%) were too incapacitated by coexistent medical disease to respond to the questionnaires. Thirty‐eight patients were not available for follow‐up, despite numerous invitations. Thirteen of the laser patients (18%) and 11 of the TURP patients (14.5%) had undergone re‐operation. Two patients from each arm had received α‐blockers for worsening symptoms. Conclusions Five years after prostatic surgery, a significant number of patients were dead or disabled by coexistent medical disease. The re‐operation rate after TURP and contact laser prostatectomy were similar.