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Female urethral carcinoma: an analysis of treatment outcome and a plea for a standardized management strategy
Author(s) -
Dalbagni,
ZuoFeng Zhang,
Louis Lacombe,
. Herr
Publication year - 1998
Publication title -
british journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 0007-1331
DOI - 10.1046/j.1464-410x.1998.00878.x
Subject(s) - medicine , univariate analysis , stage (stratigraphy) , multivariate analysis , carcinoma , surgery , interquartile range , survival analysis , disease , oncology , biology , paleontology
Objective To evaluate our experience with primary carcinomas of the female urethra, by analysing the impact of tumour variables and treatment on overall, disease‐specific, local recurrence‐ and metastasis‐free survival. Patients and methods Between 1958 and 1994, 72 women (median age 60 years, mean 59, range 21–84) with primary urethral carcinoma were identified. They were followed for a median (range) of 85 (0–384) months. The patients were stratified by stage, nodal status, histology, treatment, type of surgery, site of disease, year of diagnosis and smoking habit. Results In a univariate analysis, stage, nodal status, type of surgery and site of the disease were important factors for survival and recurrence. In a multivariate analysis, primary stage, nodal status and site of disease were independent predictors of survival. Conclusion Current modalities of treatment are ineffective for local control and survival; new treatment strategies are needed for female urethral cancers.