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Dexamethasone‐induced exophthalmos in a group of Holstein calves
Author(s) -
Townsend Wendy M.,
Renninger Matthew,
Stiles Jean,
Townsend Jonathan R.,
Krohne Sheryl G.
Publication year - 2003
Publication title -
veterinary ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.594
H-Index - 50
eISSN - 1463-5224
pISSN - 1463-5216
DOI - 10.1046/j.1463-5224.2003.00287.x
Subject(s) - exophthalmos , dexamethasone , adipose tissue , medicine , endocrinology , surgery
Six Holstein calves were evaluated for progressive exophthalmos. The affected calves were receiving daily injections of dexamethasone (30 µg/kg subcutaneously twice daily) as part of a metabolic study. The control calves did not exhibit exophthalmos. The ocular examinations were normal except for the exophthalmos, which ranged from mild to marked in severity. Upon postmortem examination, marked deposition of retrobulbar adipose tissue was noted in the affected calves. Dexamethasone administration appears to increase deposition of retrobulbar adipose tissue resulting in a progressive exophthalmos.