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Keratitis due to Histoplasma spp. in a horse
Author(s) -
Richter Marianne,
Hauser Beat,
Kaps Simone,
Spiess Bernhard M.
Publication year - 2003
Publication title -
veterinary ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.594
H-Index - 50
eISSN - 1463-5224
pISSN - 1463-5216
DOI - 10.1046/j.1463-5224.2003.00286.x
Subject(s) - histoplasma capsulatum , basophilic , histoplasma , keratitis , cornea , histoplasmosis , horse , fluconazole , biology , pathology , dermatology , microbiology and biotechnology , medicine , antifungal , ophthalmology , paleontology
A 5‐year‐old Holsteiner gelding from Germany was presented 2 months after a whitish discoloration of the left cornea was observed. Cytologic examination revealed intra‐ and extracellular globular structures, up to 4 µm in size, consisting of a central spherical deeply basophilic body surrounded by an unstained halo. The structures were morphologically consistent with Histoplasma spp. Infection with Histoplasma organisms is not endemic in Europe. Topical use of fluconazole was successful in eliminating Histoplasma organisms within 10 days of initiation of treatment.