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Equine conjunctival pseudotumors
Author(s) -
Moore Cecil P.,
Grevan Victoria L.,
Champagne Erin S.,
Collins B. Keith,
Collier Linda L.
Publication year - 2000
Publication title -
veterinary ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.594
H-Index - 50
eISSN - 1463-5224
pISSN - 1463-5216
DOI - 10.1046/j.1463-5224.2000.3230057.x
Subject(s) - eyelid , medicine , pathology , pathogenesis , peripheral blood mononuclear cell , mononuclear cell infiltration , conjunctiva , inflammation , biology , ophthalmology , immunology , biochemistry , in vitro
Five horses presented with unilateral pink, smooth, nonulcerated conjunctival masses with histologic features characteristic of inflammatory pseudotumors, i.e. proliferative inflammatory lesions clinically resembling true neoplasia. Although causes for the inflammatory lesions were not determined, based on the presence histologically of mononuclear (predominantly lymphocytic) inflammatory cell infiltrates and the absence of infectious agents, parasites or foreign bodies, an immune‐mediated pathogenesis was suspected. Affected horses ranged from 5 to 8 years of age with no apparent breed or sex predilection. Conjunctival lesions were nodular in two cases and relatively flat and more diffuse in three cases. Third eyelid lesions were present in three cases and two affected eyes had corneal involvement. Based on findings from these five cases, the prognosis for equine conjunctival pseudotumors appears to be good when lesions are treated by partial or complete surgical excision, local administration of anti‐inflammatory agents, or a combination of surgery and anti‐inflammatory therapy.