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Evaluation of intraocular and partial CO 2 pressure in dogs anesthetized with propofol
Author(s) -
Batista C.M.,
Laus J.L.,
Nunes N.,
Patto dos Santos P.S.,
Costa J.L.O.
Publication year - 2000
Publication title -
veterinary ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.594
H-Index - 50
eISSN - 1463-5224
pISSN - 1463-5216
DOI - 10.1046/j.1463-5224.2000.00099.x
Subject(s) - propofol , intraocular pressure , medicine , anesthesia , ophthalmology
The effects of propofol on intraocular pressure (IOP) and end tidal CO 2 (ETCO 2 ) were studied because an elevation in the latter may alter IOP. Twenty dogs were divided into two groups (G1 and G2). G1 dogs were induced with 10 mg/kg (IV) of propofol followed by a 0.4 mg/kg/min continuous infusion of the same agent diluted in a 0.2% dextrose solution for 1 h. G(CAPS) 2 dogs served as the control group, where only dextrose solution was administered, under the same time intervals as in G1. Applanation tonometry (Tono‐Pen) was used to determine IOP and ETCO 2 as a method to determine partial CO 2 pressure. Measurements were taken every 15 min for 1 h, with M1 occurring immediately before IV administration. IOP and ETCO 2 were not statistically significant in either groups. Based on the results, it may be concluded that propofol does not alter IOP and ETCO 2 .