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Spontaneous buphthalmos in the Djungarian hamster ( Phodopus sungorus campbelli )
Author(s) -
Ekesten Björn,
Dubielzig Richard R.
Publication year - 1999
Publication title -
veterinary ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.594
H-Index - 50
eISSN - 1463-5224
pISSN - 1463-5216
DOI - 10.1046/j.1463-5224.1999.00095.x
Subject(s) - atrophy , phodopus , retina , glaucoma , hamster , optic nerve , anatomy , ophthalmology , medicine , biology , neuroscience
Four Djungarian hamsters ( Phodopus sungorus campbelli ) were examined because of insidious globe enlargement, visual impairment and secondary altered behavior. Buphthalmos, deep anterior chambers, widely dilated pupils and poor to absent pupillary light reflexes were evident bilaterally in all four animals. Pale retinae and atrophic optic nerve heads were observed in the oldest hamsters. Light microscopic findings, including uveal atrophy, retinal atrophy (especially the inner retina), and a relative decrease in ganglion cells and optic nerve atrophy, were consistent with glaucoma. The etiology was unclear, but a genetic predisposition cannot be excluded.