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Pathophysiology of the Pulmonary Vein as an Atrial Fibrillation Initiator:
Author(s) -
CHEN SHIHANN,
CHEN YIJEN,
YEH HUNGI,
TAI CHINGTAI,
CHEN YAOCHANG,
LIN CHENGI
Publication year - 2003
Publication title -
pacing and clinical electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 101
eISSN - 1540-8159
pISSN - 0147-8389
DOI - 10.1046/j.1460-9592.2003.t01-1-00235.x
Subject(s) - medicine , atrial fibrillation , pulmonary vein , cardiology , pathophysiology , vein , automaticity , atrium (architecture) , electrical conduction system of the heart , electrocardiography , cognition , psychiatry
The basic electrophysiologic studies have proved the arrhythmogenic mechanisms of the pulmonary vein as an atrial fibrillation initiator; the mechanisms include enhanced automaticity, triggered activity, and microreentry from myocardial sleeves inside pulmonary veins. Immunohistology study has proved the conduction characteristics of pulmonary vein myocardium, and further study of ionic currents are important for understanding atrial fibrillation initiation from the pulmonary vein. (PACE 2003; 26[Pt. II]:1576–1582)