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Lacticacidosis after short‐term infusion of propofol for anaesthesia in a child with osteogenesis imperfecta
Author(s) -
Kill Clemens,
Leonhardt Andreas,
Wulf Hinnerk
Publication year - 2003
Publication title -
pediatric anesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.704
H-Index - 82
eISSN - 1460-9592
pISSN - 1155-5645
DOI - 10.1046/j.1460-9592.2003.01114.x
Subject(s) - medicine , propofol , anesthesia , osteogenesis imperfecta , discontinuation , fentanyl , surgery , femur , anatomy
Summary We describe the case of a 7‐year‐old boy with osteogenesis imperfecta, who underwent anaesthesia with propofol–fentanyl–nitrous oxide–suxamethonium for orthopaedic surgery of a distal femur fracture. He developed lacticacidosis after short‐term propofol infusion (150 min, mean infusion rate 13.5 mg·kg −1 ·h −1 ) associated with a prolonged recovery time without serious haemodynamic changes. The highest lactate concentration was 9.2 mmol·l −1 at 160 min after discontinuation of propofol. There was no significant increase in body temperature. The boy fully recovered.

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