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Electrical Alternans In Long QT Syndrome Resembling a Brugada Syndrome Pattern
Author(s) -
SCHULZEBAHR ERIC,
ZOELCH KARLALBERT,
ECKARDT LARS,
HAVERKAMP WILHELM,
BREITHARDT GÜNTER,
BORGGREFE MARTIN
Publication year - 2003
Publication title -
pacing and clinical electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 101
eISSN - 1540-8159
pISSN - 0147-8389
DOI - 10.1046/j.1460-9592.2003.00313.x
Subject(s) - brugada syndrome , t wave alternans , medicine , repolarization , long qt syndrome , qrs complex , cardiology , qt interval , j wave , electrocardiography , depolarization , sudden cardiac death , electrophysiology
Isolated T wave alternans (repolarization alternans) is frequently associated with long QT syndrome. However, electrical alternans involving the P wave, QRS complex, ST segment (depolarization alternans), and the T wave is a rare finding. This report describes a 62‐year‐old women with long QT syndrome and an electrical alternans occurring after previous syncope. Alternating QRS complexes showed a prolonged PR interval, a Brugada syndrome resembling pattern of the QRS complexes (elevation and downslope of the ST segments), and a T wave alternans. A genetic basis for the long QT syndrome has been ruled out by sequencing of all coding areas of the LQT genes. Potential mechanisms for the electrical alternans are discussed. (PACE 2003; 26:2033–2035)