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Autonomic Tone in Patients with Supraventricular Arrhythmia Associated with Mitral Valve Prolapse in Young Men
Author(s) -
TERECHTCHENKO LARISSA,
DORONINA SVETLANA A.,
POCHINOK ELENA M.,
RIFTINE ALEXANDER
Publication year - 2003
Publication title -
pacing and clinical electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 101
eISSN - 1540-8159
pISSN - 0147-8389
DOI - 10.1046/j.1460-9592.2003.00067.x
Subject(s) - medicine , supraventricular arrhythmia , mitral valve prolapse , cardiology , vagal tone , heart rate variability , ambulatory , incidence (geometry) , electrocardiography , heart rate , mitral valve , atrial fibrillation , blood pressure , physics , optics
TERECHTCHENKO, L., et al .: Autonomic Tone in Patients with Supraventricular Arrhythmia Associated with Mitral Valve Prolapse in Young Men.This study examined the relation between autonomic tone and the frequency and duration of supraventricular arrhythmias (SVA) in 44 men (mean age17 ± 5years) with mitral valve prolapse (MVP), confirmed by echocardiography. Ambulatory and short‐term electrocardiograms (ECG) were recorded, and transesophageal pacing was performed. Frequency domain heart rate variability (HRV) indices were obtained from short‐term ECG recordings at rest and during postural stress. Results: In 14 patients, the index of parasympathetic activity was significantly higher (2.1 ± 0,01vs‐1.5 ± 0.01, P < 0.01), and associated with a high incidence of vagally‐mediated SVA. The frequency of SV premature beats in patients with parasympathetic prevalence was58 ± 86/hourversus10 ± 27/hourin patients with sympathetic prevalence( P < 0.05 ) . In 30 patients with high sympathetic activity, the index of sympathetic tone was significantly higher ( 3.1 ± 0.01 vs 0.5 ± 0.01 ) and the high frequency/low frequency ratio significantly lower ( 0.294 ± 0.03 vs 0.581 ± 0.02, P < 0.05 ), though the incidence of SVA was significantly lower and duration shorter. The algorithm allowed the noninvasive quantitative assessment of autonomic activity and mechanism behind the development of SVA, which may help in the choice of treatment. (PACE 2003; 26[Pt. II]:444–446)