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Catecholaminergic Polymorphic Ventricular Tachycardia in a 3‐Year‐Old with Occult Myocarditis
Author(s) -
BRYANT RANDALL M.,
REDFEARN SHARON P.,
MARANGI DON,
DAVENPORT JOSEPH P.,
KUNTZ SEAN T.,
SCHOWENGERDT KENNETH O.
Publication year - 2002
Publication title -
pacing and clinical electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 101
eISSN - 1540-8159
pISSN - 0147-8389
DOI - 10.1046/j.1460-9592.2002.01520.x
Subject(s) - catecholaminergic polymorphic ventricular tachycardia , medicine , cardiology , occult , myocarditis , ventricular tachycardia , ventricular fibrillation , tachycardia , pathology , ryanodine receptor 2 , ryanodine receptor , calcium , alternative medicine
BRYANT, R.M., et al. : Catecholaminergic Polymorphic Ventricular Tachycardia in a 3‐Year‐Old with Occult Myocarditis. Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a rare clinical entity in children. Occult myocarditis has not been previously implicated as an etiologic agent. A 3‐year‐old female presents with a presumed breath‐holding spell and is found to have ventricular fibrillation requiring DC cardioversion. An invasive electrophysiological study was performed demonstrating the absence of inducible ventricular arrhythmias. Low dose epinephrine confirmed the presence CPVT. Right ventricular endomyocardial biopsies sent for polymerase chain reaction (PCR) analysis demonstrated the presence of adenoviral DNA. The authors hypothesize that occult myocarditis may be the inciting agent for CPVT in children.