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Anaesthesia with sevoflurane in children: nitrous oxide does not increase postoperative vomiting
Author(s) -
Bortone Luciano,
Picetti Edoardo,
Mergoni Mario
Publication year - 2002
Publication title -
pediatric anesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.704
H-Index - 82
eISSN - 1460-9592
pISSN - 1155-5645
DOI - 10.1046/j.1460-9592.2002.00939.x
Subject(s) - medicine , nitrous oxide , sevoflurane , anesthesia , vomiting , postoperative nausea and vomiting
Summary Background : Nitrous oxide (N 2 O) has been associated with postoperative nausea and vomiting (PONV), but some studies show conflicting data. The aim of this study was to assess whether the combination of N 2 O/sevoflurane, in paediatric general anaesthesia, increases the incidence of vomiting in the 24 h following surgery compared with sevoflurane alone. Methods : One hundred and fourteen children, aged 1–10 years, who underwent testicle and inguinal hernia surgery, were randomized to receive one of the following two anaesthetic regimens: sevoflurane with 70% N 2 O (group A) or sevoflurane alone (group B). Results : No significant differences were observed in the incidence of postoperative vomiting between the two groups. The overall incidence of postoperative vomiting was 14.9%; 14.3% in group A and 15.5% in group B ( P =0.9). Conclusions : Nitrous oxide used in combination with sevoflurane is not associated with an increase in the incidence of emesis in children who undergo testicle and inguinal hernia procedures.